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Reengineering Human Bruch's Membrane Increases Rod Outer Segment Phagocytosis by Human Retinal Pigment Epithelium

PURPOSE: We have shown previously that Bruch's membrane (BM) aging decreases retinal pigment epithelium (RPE) phagocytosis. Herein, we determine the effects of BM reengineering on RPE phagocytosis. METHODS: BM explants were dissected from young and old donor eyes. Some old BM explants were reen...

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Detalhes bibliográficos
Publicado no:Transl Vis Sci Technol
Main Authors: Moreira, Ernesto F., Cai, Hui, Tezel, Tongalp H., Fields, Mark A., Del Priore, Lucian V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633034/
https://ncbi.nlm.nih.gov/pubmed/26557417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.4.5.10
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