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Phagocytosis-dependent ketogenesis in retinal pigment epithelium

Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipid and protein in the form of phagocytized photoreceptor outer segments (OS). The RPE, like the liver, expresses enzymes required for fatty acid oxidation and ketogenesis. This suggests that these pathways play a role in the disposal...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Reyes-Reveles, Juan, Dhingra, Anuradha, Alexander, Desiree, Bragin, Alvina, Philp, Nancy J., Boesze-Battaglia, Kathleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427279/
https://ncbi.nlm.nih.gov/pubmed/28302729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770784
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