Phagocytosis-dependent ketogenesis in retinal pigment epithelium

Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipid and protein in the form of phagocytized photoreceptor outer segments (OS). The RPE, like the liver, expresses enzymes required for fatty acid oxidation and ketogenesis. This suggests that these pathways play a role in the disposal...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Reyes-Reveles, Juan, Dhingra, Anuradha, Alexander, Desiree, Bragin, Alvina, Philp, Nancy J., Boesze-Battaglia, Kathleen
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427279/
https://ncbi.nlm.nih.gov/pubmed/28302729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770784
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