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Phagocytosis-dependent ketogenesis in retinal pigment epithelium

Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipid and protein in the form of phagocytized photoreceptor outer segments (OS). The RPE, like the liver, expresses enzymes required for fatty acid oxidation and ketogenesis. This suggests that these pathways play a role in the disposal...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Reyes-Reveles, Juan, Dhingra, Anuradha, Alexander, Desiree, Bragin, Alvina, Philp, Nancy J., Boesze-Battaglia, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427279/
https://ncbi.nlm.nih.gov/pubmed/28302729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770784
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