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The Sjögren’s syndrome‐associated autoantigen Ro52/TRIM21 modulates follicular B cell homeostasis and immunoglobulin production

Systemic rheumatic diseases are characterized by abnormal B cell activation with autoantibody production and hypergammaglobulinaemia. Ro52/SSA, also denoted tripartite motif (TRIM)21, is a major autoantigen in Sjögren’s syndrome and systemic lupus erythematosus. Interestingly, TRIM21‐deficient mice...

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Bibliografiske detaljer
Udgivet i:Clin Exp Immunol
Main Authors: Brauner, S., Ivanchenko, M., Thorlacius, G. E., Ambrosi, A., Wahren‐Herlenius, M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230998/
https://ncbi.nlm.nih.gov/pubmed/30178506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13211
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