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The Sjögren’s syndrome‐associated autoantigen Ro52/TRIM21 modulates follicular B cell homeostasis and immunoglobulin production
Systemic rheumatic diseases are characterized by abnormal B cell activation with autoantibody production and hypergammaglobulinaemia. Ro52/SSA, also denoted tripartite motif (TRIM)21, is a major autoantigen in Sjögren’s syndrome and systemic lupus erythematosus. Interestingly, TRIM21‐deficient mice...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6230998/ https://ncbi.nlm.nih.gov/pubmed/30178506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13211 |
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