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Liquid and Hydrogel Phases of PrP(C) Linked to Conformation Shifts and Triggered by Alzheimer’s Amyloid-β Oligomers
Protein phase separation by low complexity, intrinsically disordered domains generates membraneless organelles and links to neurodegeneration. Cellular prion protein (PrP(C)) contains such domains, causes spongiform degeneration and is a receptor for Alzheimer’s amyloid-β oligomers (Aβo). Here, we s...
में बचाया:
में प्रकाशित: | Mol Cell |
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मुख्य लेखकों: | , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2018
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6226277/ https://ncbi.nlm.nih.gov/pubmed/30401430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.10.009 |
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