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The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease

The SLC22 transporter family consists of more than two dozen members, which are expressed in the kidney, the liver, and other tissues. Evolutionary analysis indicates that SLC22 transporters fall into at least six subfamilies: OAT (organic anion transporter), OAT-like, OAT-related, OCT (organic cati...

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Bibliographic Details
Published in:Annu Rev Pharmacol Toxicol
Main Author: Nigam, Sanjay K.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225997/
https://ncbi.nlm.nih.gov/pubmed/29309257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010617-052713
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