Attaching the NorA Efflux Pump Inhibitor INF55 to Methylene Blue Enhances Antimicrobial Photodynamic Inactivation of Methicillin-Resistant Staphylococcus aureus in Vitro and in Vivo

Antimicrobial photodynamic inactivation (aPDI) uses photosensitizers (PSs) and harmless visible light to generate reactive oxygen species (ROS) and kill microbes. Multidrug efflux systems can moderate the phototoxic effects of PSs by expelling the compounds from cells. We hypothesized that increasin...

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Pubblicato in:ACS Infect Dis
Autori principali: Rineh, Ardeshir, Dolla, Naveen K., Ball, Anthony R., Magana, Maria, Bremner, John B., Hamblin, Michael R., Tegos, George P., Kelso, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225778/
https://ncbi.nlm.nih.gov/pubmed/28799332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00095
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