Berberine-INF55 (5-Nitro-2-Phenylindole) Hybrid Antimicrobials: Effects of Varying the Relative Orientation of the Berberine and INF55 Components

Hybrid antimicrobials containing an antibacterial linked to a multidrug resistance (MDR) pump inhibitor make up a promising new class of agents for countering efflux-mediated bacterial drug resistance. This study explores the effects of varying the relative orientation of the antibacterial and efflu...

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Detalhes bibliográficos
Main Authors: Tomkiewicz, Danuta, Casadei, Gabriele, Larkins-Ford, Jonah, Moy, Terence I., Garner, James, Bremner, John B., Ausubel, Frederick M., Lewis, Kim, Kelso, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916310/
https://ncbi.nlm.nih.gov/pubmed/20498327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01715-09
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