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HCN Channels: New Therapeutic Targets for Pain Treatment

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are highly regulated proteins which respond to different cellular stimuli. The HCN currents (I(h)) mediated by HCN1 and HCN2 drive the repetitive firing in nociceptive neurons. The role of HCN channels in pain has been widely investi...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Ramírez, David, Zúñiga, Rafael, Concha, Guierdy, Zúñiga, Leandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225464/
https://ncbi.nlm.nih.gov/pubmed/30134541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092094
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