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The Insensitivity of TASK-3 K(2)P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure

Two-pore domain K(+) channels (K(2)P) display a characteristic extracellular cap structure formed by two M1-P1 linkers, the functional role of which is poorly understood. It has been proposed that the presence of the cap explains the insensitivity of K(2)P channels to several K(+) channel blockers i...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Concha, Guierdy, Bustos, Daniel, Zúñiga, Rafael, Catalán, Marcelo A., Zúñiga, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121469/
https://ncbi.nlm.nih.gov/pubmed/30126179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082437
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