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HCN and K(V)7 (M-) channels as targets for epilepsy treatment

Voltage-gated ion channels are important determinants of cellular excitability. The Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) and K(V)7 (M-) channels are voltage-gated ion channels. Both channels are activated at sub-threshold potentials and have biophysical properties that mirror ea...

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Bibliographic Details
Main Authors: Shah, Mala M., Huang, Zhuo, Martinello, Katiuscia
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104618/
https://ncbi.nlm.nih.gov/pubmed/22446478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.03.005
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