Sinomenine Protects Against Morphine Dependence through the NMDAR1/CAMKII/CREB Pathway: A Possible Role of Astrocyte-Derived Exosomes

Sinomenine is a nonaddictive alkaloid used to prevent morphine dependence, even thoughits mechanism isnot fully understood. Astrocytes aggravate the pathological process in their neighboring cellsthrough exosomes in central nervous system diseases. However, the effect of sinomenine on astrocyte-deri...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Ou, Jinying, Zhou, Yuting, Li, Chan, Chen, Zhijie, Li, Hancheng, Fang, Miao, Zhu, Chen, Huo, Chuying, Yung, Ken Kin-Lam, Li, Jing, Luo, Chaohua, Mo, Zhixian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225372/
https://ncbi.nlm.nih.gov/pubmed/30227624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092370
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