Sinomenine Protects Against Morphine Dependence through the NMDAR1/CAMKII/CREB Pathway: A Possible Role of Astrocyte-Derived Exosomes

Sinomenine is a nonaddictive alkaloid used to prevent morphine dependence, even thoughits mechanism isnot fully understood. Astrocytes aggravate the pathological process in their neighboring cellsthrough exosomes in central nervous system diseases. However, the effect of sinomenine on astrocyte-deri...

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Vydáno v:Molecules
Hlavní autoři: Ou, Jinying, Zhou, Yuting, Li, Chan, Chen, Zhijie, Li, Hancheng, Fang, Miao, Zhu, Chen, Huo, Chuying, Yung, Ken Kin-Lam, Li, Jing, Luo, Chaohua, Mo, Zhixian
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225372/
https://ncbi.nlm.nih.gov/pubmed/30227624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092370
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