Sinomenine Protects Against Morphine Dependence through the NMDAR1/CAMKII/CREB Pathway: A Possible Role of Astrocyte-Derived Exosomes

Sinomenine is a nonaddictive alkaloid used to prevent morphine dependence, even thoughits mechanism isnot fully understood. Astrocytes aggravate the pathological process in their neighboring cellsthrough exosomes in central nervous system diseases. However, the effect of sinomenine on astrocyte-deri...

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Pubblicato in:Molecules
Autori principali: Ou, Jinying, Zhou, Yuting, Li, Chan, Chen, Zhijie, Li, Hancheng, Fang, Miao, Zhu, Chen, Huo, Chuying, Yung, Ken Kin-Lam, Li, Jing, Luo, Chaohua, Mo, Zhixian
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225372/
https://ncbi.nlm.nih.gov/pubmed/30227624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092370
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