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Multi-Body Interactions in Molecular Docking Program Devised with Key Water Molecules in Protein Binding Sites

Water molecules play an important role in modeling protein-ligand interactions. However, traditional molecular docking methods often ignore the impact of the water molecules by removing them without any analysis or keeping them as a static part of the proteins or the ligands. Hence, the accuracy of...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Xiao, Wei, Wang, Disha, Shen, Zihao, Li, Shiliang, Li, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225211/
https://ncbi.nlm.nih.gov/pubmed/30208655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092321
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