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RD-Metabolizer: an integrated and reaction types extensive approach to predict metabolic sites and metabolites of drug-like molecules

BACKGROUND: Experimental approaches for determining the metabolic properties of the drug candidates are usually expensive, time-consuming and labor intensive. There is a great deal of interest in developing computational methods to accurately and efficiently predict the metabolic decomposition of dr...

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Podrobná bibliografie
Vydáno v:Chem Cent J
Hlavní autoři: Meng, Jiajia, Li, Shiliang, Liu, Xiaofeng, Zheng, Mingyue, Li, Honglin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515729/
https://ncbi.nlm.nih.gov/pubmed/29086838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0290-4
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