Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia

Chronic inflammation is a pathophysiology of insulin resistance in metabolic diseases, such as obesity and type 2 diabetes. Adipose tissue macrophages (ATMs) play important roles in this inflammatory process. SIRT1 is implicated in the regulation of glucose metabolism in some metabolic tissues, such...

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Enregistré dans:
Détails bibliographiques
Publié dans:Diabetol Int
Auteurs principaux: Takikawa, Akiko, Usui, Isao, Fujisaka, Shiho, Ikutani, Masashi, Senda, Satoko, Hattori, Shinpei, Tsuneyama, Koichi, Koshimizu, Yukiko, Inoue, Ran, Tanaka-Hayashi, Ayumi, Nakagawa, Takashi, Nagai, Yoshinori, Takatsu, Kiyoshi, Sasaoka, Toshiyasu, Mori, Hisashi, Tobe, Kazuyuki
Format: Artigo
Langue:Inglês
Publié: Springer Japan 2015
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224900/
https://ncbi.nlm.nih.gov/pubmed/30603244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13340-015-0213-3
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