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The I(Ks) Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry
The delayed potassium rectifier current, I(Ks,) is assembled from tetramers of KCNQ1 and varying numbers of KCNE1 accessory subunits in addition to calmodulin. This channel complex is important in the response of the cardiac action potential to sympathetic stimulation, during which I(Ks) is enhanced...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224683/ https://ncbi.nlm.nih.gov/pubmed/30314657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.09.018 |
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