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Structural basis for the second step of group II intron splicing
The group II intron and the spliceosome share a common active site architecture and are thought to be evolutionarily related. Here we report the 3.7 Å crystal structure of a eukaryotic group II intron in the lariat-3′ exon form, immediately preceding the second step of splicing, analogous to the spl...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224600/ https://ncbi.nlm.nih.gov/pubmed/30410046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06678-0 |
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