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Crystal structure of a eukaryotic group II intron lariat

The formation of branched lariat RNA is an evolutionarily conserved feature of splicing reactions for both group II and spliceosomal introns. The lariat is important for the fidelity of 5′ splice site selection and consists of a 2′-5′ phosphodiester bond between a bulged adenosine and the 5′ end of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Robart, Aaron R., Chan, Russell T., Peters, Jessica K., Rajashankar, Kanagalaghatta R., Toor, Navtej
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197185/
https://ncbi.nlm.nih.gov/pubmed/25252982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13790
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