Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors

IMPORTANCE: Although clonal hematopoiesis (CH) is well described in aging healthy populations, few studies have addressed the practical clinical implications of these alterations in solid-tumor sequencing. OBJECTIVE: To identify and quantify CH-related mutations in patients with solid tumors using m...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Ptashkin, Ryan N., Mandelker, Diana L., Coombs, Catherine C., Bolton, Kelly, Yelskaya, Zarina, Hyman, David M., Solit, David B., Baselga, José, Arcila, Maria E., Ladanyi, Marc, Zhang, Liying, Levine, Ross L., Berger, Michael F., Zehir, Ahmet
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224316/
https://ncbi.nlm.nih.gov/pubmed/29872864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.2297
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