Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors

IMPORTANCE: Although clonal hematopoiesis (CH) is well described in aging healthy populations, few studies have addressed the practical clinical implications of these alterations in solid-tumor sequencing. OBJECTIVE: To identify and quantify CH-related mutations in patients with solid tumors using m...

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Vydáno v:JAMA Oncol
Hlavní autoři: Ptashkin, Ryan N., Mandelker, Diana L., Coombs, Catherine C., Bolton, Kelly, Yelskaya, Zarina, Hyman, David M., Solit, David B., Baselga, José, Arcila, Maria E., Ladanyi, Marc, Zhang, Liying, Levine, Ross L., Berger, Michael F., Zehir, Ahmet
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2018
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224316/
https://ncbi.nlm.nih.gov/pubmed/29872864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.2297
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