Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer

Cervical cancer development following a persistent infection with high-risk human papillomavirus (hrHPV) is driven by additional host-cell changes, such as altered DNA methylation. In previous studies, we have identified 12 methylated host genes associated with cervical cancer and pre-cancer (CIN2/3...

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Vydáno v:Epigenetics
Hlavní autoři: Verlaat, Wina, Van Leeuwen, Robert W., Novianti, Putri W., Schuuring, Ed, Meijer, Chris J. L. M., Van Der Zee, Ate G. J., Snijders, Peter J. F., Heideman, Daniëlle A. M., Steenbergen, Renske D. M., Wisman, G. Bea A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224221/
https://ncbi.nlm.nih.gov/pubmed/30079796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1507197
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