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Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases

ω3‐polyunsaturated free fatty acids (ω3‐PUFAs), particularly docosahexaenoic (DHA) and eicosapentaenoic acid (EPA), are thought to exert health promoting effects in metabolic and in inflammatory diseases. The molecular mechanisms of these beneficial effects are only partially understood. DHA and EPA...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Wannick, Melanie, Bezdek, Siegfried, Guillen, Nathalie, Thieme, Markus, Meshrkey, Fibi, Mousavi, Sadegh, Seeling, Michaela, Nimmerjahn, Falk, Mócsai, Attila, Zillikens, Detlef, Sezin, Tanya, Sadik, Christian D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223243/
https://ncbi.nlm.nih.gov/pubmed/30455959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.438
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