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Renal Soluble Guanylate Cyclase Is Downregulated in Sunitinib‐Induced Hypertension
BACKGROUND: The tyrosine kinase inhibitor sunitinib causes hypertension associated with reduced nitric oxide (NO) availability, elevated renal vascular resistance, and decreased fractional sodium excretion. We tested whether (1) nitrate supplementation mitigates sunitinib‐induced hypertension and NO...
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| 出版年: | J Am Heart Assoc |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6222942/ https://ncbi.nlm.nih.gov/pubmed/30371202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009557 |
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