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Targeting soluble guanylate cyclase for the treatment of pulmonary hypertension

Pulmonary arterial hypertension is a disease characterized by a sustained increase in pulmonary arterial pressure leading to right heart failure. Current treatments focus on endothelial dysfunction and an aberrant regulatory pathway for vascular tone. Unfortunately, a large proportion of patients ar...

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Detalhes bibliográficos
Main Authors: Lasker, George F, Maley, Jason H, Pankey, Edward A, Kadowitz, Philip J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108035/
https://ncbi.nlm.nih.gov/pubmed/21510726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/ers.11.9
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