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Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling
Transient mitochondrial stress can promote beneficial physiological responses and longevity, termed “mitohormesis.” To interrogate mitohormetic pathways in mammals, we generated mice in which mitochondrial superoxide dismutase 2 (SOD2) can be knocked-down in an inducible and reversible manner (iSOD2...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6221994/ https://ncbi.nlm.nih.gov/pubmed/30122556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.07.011 |
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