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Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness

Mitochondrial biogenesis is controlled by signaling networks that relay information to and from the organelles. However, key mitochondrial factors that mediate such pathways and how they contribute to human disease are not understood fully. Here we demonstrate that the rRNA methyltransferase-related...

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Detalhes bibliográficos
Main Authors: Cotney, Justin, McKay, Sharen E., Shadel, Gerald S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701340/
https://ncbi.nlm.nih.gov/pubmed/19417006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp208
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