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Bias in Mendelian randomization due to assortative mating

Mendelian randomization (MR) has been increasingly used to strengthen causal inference in observational epidemiology. Methodological developments in the field allow detecting and/or adjusting for different potential sources of bias, mainly bias due to horizontal pleiotropy (or “off‐target” genetic e...

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Bibliografske podrobnosti
izdano v:Genet Epidemiol
Main Authors: Hartwig, Fernando Pires, Davies, Neil Martin, Davey Smith, George
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221130/
https://ncbi.nlm.nih.gov/pubmed/29971821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22138
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