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Bias due to participant overlap in two‐sample Mendelian randomization

Mendelian randomization analyses are often performed using summarized data. The causal estimate from a one‐sample analysis (in which data are taken from a single data source) with weak instrumental variables is biased in the direction of the observational association between the risk factor and outc...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Burgess, Stephen, Davies, Neil M., Thompson, Simon G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082560/
https://ncbi.nlm.nih.gov/pubmed/27625185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21998
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