NADPH Oxidase 5 Is a Pro‐Contractile Nox Isoform and a Point of Cross‐Talk for Calcium and Redox Signaling‐Implications in Vascular Function

BACKGROUND: NADPH Oxidase 5 (Nox5) is a calcium‐sensitive superoxide‐generating Nox. It is present in lower forms and higher mammals, but not in rodents. Nox5 is expressed in vascular cells, but the functional significance remains elusive. Given that contraction is controlled by calcium and reactive...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Montezano, Augusto C., De Lucca Camargo, Livia, Persson, Patrik, Rios, Francisco J., Harvey, Adam P., Anagnostopoulou, Aikaterini, Palacios, Roberto, Gandara, Ana Caroline P., Alves‐Lopes, Rheure, Neves, Karla B., Dulak‐Lis, Maria, Holterman, Chet E., de Oliveira, Pedro Lagerblad, Graham, Delyth, Kennedy, Christopher, Touyz, Rhian M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220544/
https://ncbi.nlm.nih.gov/pubmed/29907654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009388
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