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Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells

Vascular smooth muscle cell (VSMC) function is regulated by Nox-derived reactive oxygen species (ROS) and redox-dependent signaling in discrete cellular compartments. Whether cholesterol-rich microdomains (lipid rafts/caveolae) are involved in these processes is unclear. Here we examined the sub-cel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Anagnostopoulou, Aikaterini, Camargo, Livia L., Rodrigues, Daniel, Montezano, Augusto C., Touyz, Rhian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575553/
https://ncbi.nlm.nih.gov/pubmed/33082354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73751-4
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