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Quantification of Hsp90 availability reveals differential coupling to the heat shock response

The heat shock response (HSR) is a protective gene expression program that is activated by conditions that cause proteotoxic stress. While it has been suggested that the availability of free chaperones regulates the HSR, chaperone availability and the HSR have never been precisely quantified in tand...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Alford, Brian D., Brandman, Onn
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219726/
https://ncbi.nlm.nih.gov/pubmed/30131327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201803127
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