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ReporterSeq reveals genome-wide dynamic modulators of the heat shock response across diverse stressors

Understanding cellular stress response pathways is challenging because of the complexity of regulatory mechanisms and response dynamics, which can vary with both time and the type of stress. We developed a reverse genetic method called ReporterSeq to comprehensively identify genes regulating a stres...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Alford, Brian D, Tassoni-Tsuchida, Eduardo, Khan, Danish, Work, Jeremy J, Valiant, Gregory, Brandman, Onn
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257254/
https://ncbi.nlm.nih.gov/pubmed/34223816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57376
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