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HSP90 inhibition without heat shock response
In this issue of Blood, Bhatia and colleagues describe a heat shock protein 90 (HSP90) C-terminal dimerization inhibitor with mechanistic differences that distinguish it from other clinically unsuccessful N-terminal ATPase binding compounds.(1) Can graveyard raiding of an old therapeutic target with...
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| Vydáno v: | Blood |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053952/ https://ncbi.nlm.nih.gov/pubmed/30026301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-850271 |
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