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Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

Nebulin (Neb) is associated with the thin filament in skeletal muscle cells, but its functions are not well understood. For this goal, we study skinned slow-twitch soleus muscle fibers from wild-type (Neb(+)) and conditional Neb knockout (Neb(−)) mice. We characterize cross-bridge (CB) kinetics and...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Kawai, Masataka, Karam, Tarek S., Kolb, Justin, Wang, Li, Granzier, Henk L.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219688/
https://ncbi.nlm.nih.gov/pubmed/30301869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812104
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