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Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle
Nebulin is a giant sarcomeric protein that spans along the actin filament in skeletal muscle, from the Z-disk to near the thin filament pointed end. Mutations in nebulin cause muscle weakness in nemaline myopathy patients, suggesting that nebulin plays important roles in force generation, yet little...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187167/ https://ncbi.nlm.nih.gov/pubmed/30249654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804726115 |
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