Yüklüyor......
An allosteric mechanism of inactivation in the calcium-dependent chloride channel BEST1
Bestrophin proteins are calcium (Ca(2+))-activated chloride channels. Mutations in bestrophin 1 (BEST1) cause macular degenerative disorders. Whole-cell recordings show that ionic currents through BEST1 run down over time, but it is unclear whether this behavior is intrinsic to the channel or the re...
Kaydedildi:
| Yayımlandı: | J Gen Physiol |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Rockefeller University Press
2018
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6219684/ https://ncbi.nlm.nih.gov/pubmed/30237227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812190 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|