Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption

Circulating fatty acid binding protein 4 (FABP4), secreted from adipocytes, is a potential biomarker for metabolic and cardiovascular diseases. Circulating FABP4 levels are positively associated with adiposity and adrenergic stimulation, but negatively with renal function. In this study, we addresse...

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Publicat a:Sci Rep
Autors principals: Shrestha, Suman, Sunaga, Hiroaki, Hanaoka, Hirofumi, Yamaguchi, Aiko, Kuwahara, Shoji, Umbarawan, Yogi, Nakajima, Kiyomi, Machida, Tetsuo, Murakami, Masami, Saito, Akihiko, Tsushima, Yoshito, Kurabayashi, Masahiko, Iso, Tatsuya
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219568/
https://ncbi.nlm.nih.gov/pubmed/30401801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34902-w
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