Modulating cellular autophagy for controlled antiretroviral drug release

AIM: Pharmacologic agents that affect autophagy were tested for their abilities to enhance macrophage nanoformulated antiretroviral drug (ARV) depots and its slow release. METHODS: These agents included URMC-099, rapamycin, metformin, desmethylclomipramine, 2-hydroxy-β-cyclodextrin (HBC) and clonidi...

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Dettagli Bibliografici
Pubblicato in:Nanomedicine (Lond)
Autori principali: Thomas, Midhun B, Gnanadhas, Divya Prakash, Dash, Prasanta K, Machhi, Jatin, Lin, Zhiyi, McMillan, JoEllyn, Edagwa, Benson, Gelbard, Harris, Gendelman, Howard E, Gorantla, Santhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219451/
https://ncbi.nlm.nih.gov/pubmed/30129397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2018-0224
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