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Pharmacodynamics of folic acid-receptor targeted antiretroviral nanotherapy in HIV-1-infected humanized mice

Long acting nanoformulated antiretroviral therapy (nanoART) can sustain plasma drug levels and improve its biodistribution. Cell targeted-nanoART can achieve this and bring drug efficiently to viral reservoirs. However, if such improvements affect antiretroviral responses remains unknown. To these e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antiviral Res
Hauptverfasser: Puligujja, Pavan, Araínga, Mariluz, Dash, Prasanta, Palandri, Diana, Mosley, R. Lee, Gorantla, Santhi, Poluektova, Larisa, McMillan, JoEllyn, Gendelman, Howard E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492829/
https://ncbi.nlm.nih.gov/pubmed/26026666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2015.05.009
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