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Mutational spectra and mutational signatures: Insights into cancer aetiology and mechanisms of DNA damage and repair

Reporter gene assays, in which a single mutation from each experiment can contribute to the assembly of a mutation spectrum for an agent, have provided the basis for understanding the mutational processes induced by mutagenic agents and for providing clues to the origins of mutations in human tumour...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Autor principal: Phillips, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219445/
https://ncbi.nlm.nih.gov/pubmed/30236628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.003
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