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Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells

Somatic genome instability is a hallmark of cancer genomes and has been linked to aging and a variety of other pathologies. Large-scale cancer genome and exome sequencing have revealed that mutation load and spectra in cancers can be influenced by environmental exposures, the anatomical site of expo...

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Publicado en:Environ Mol Mutagen
Autores principales: Saini, Natalie, Gordenin, Dmitry A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188803/
https://ncbi.nlm.nih.gov/pubmed/30152078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22215
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