Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain

It is clear that RhoA activates the DRF (diaphanous-related formin) mDia2 by disrupting the molecular interaction between the DAD (diaphanous autoregulatory domain) and the DID (diaphanous inhibitory domain). Previous studies indicate that a basic motif within the DAD contributes to mDia2 auto-inhib...

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Bibliographic Details
Published in:Biochem J
Main Authors: Staus, Dean P., Taylor, Joan M., Mack, Christopher P.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219394/
https://ncbi.nlm.nih.gov/pubmed/21699497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101700
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