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Loss of RhoB Expression Enhances the Myelodysplastic Phenotype of Mammalian Diaphanous-Related Formin mDia1 Knockout Mice

Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis and hyperplastic bone marrow. Complete loss or interstitial deletions of the long arm of chromosome 5 occur frequently in MDS. One candidate tumor suppressor on 5q is the mammalian Diaphanous (mDia)-related formin mDia1, en...

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Bibliografiske detaljer
Main Authors: DeWard, Aaron D., Leali, Kellie, West, Richard A., Prendergast, George C., Alberts, Arthur S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740832/
https://ncbi.nlm.nih.gov/pubmed/19768111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007102
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