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Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis

Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, its ability to trigger cell death has not been described in human spermatozo...

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Detalhes bibliográficos
Publicado no:Asian J Androl
Main Authors: Uribe, Pamela, Cabrillana, María E, Fornés, Miguel W, Treulen, Favián, Boguen, Rodrigo, Isachenko, Vladimir, Isachenko, Evgenia, Sánchez, Raúl, Villegas, Juana V
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219306/
https://ncbi.nlm.nih.gov/pubmed/29956685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_29_18
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