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Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis

Cyclophilin-D is a peptidylprolyl cis–trans isomerase of the mitochondrial matrix. It is involved in mitochondrial permeability transition, in which the adenine nucleotide translocase of the inner membrane is transformed from an antiporter to a non-selective pore. The permeability transition has bee...

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Bibliografiske detaljer
Main Authors: Li, Yanmin, Johnson, Nicholas, Capano, Michela, Edwards, Mina, Crompton, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134048/
https://ncbi.nlm.nih.gov/pubmed/15233627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040669
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