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Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis
Cyclophilin-D is a peptidylprolyl cis–trans isomerase of the mitochondrial matrix. It is involved in mitochondrial permeability transition, in which the adenine nucleotide translocase of the inner membrane is transformed from an antiporter to a non-selective pore. The permeability transition has bee...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134048/ https://ncbi.nlm.nih.gov/pubmed/15233627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040669 |
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