M3 muscarinic acetylcholine receptors regulate epithelial–mesenchymal transition, perineural invasion, and migration/metastasis in cholangiocarcinoma through the AKT pathway

BACKGROUND: Cholangiocarcinoma is a highly malignant tumor type that is not sensitive to radiotherapy or chemotherapy due to aggressive perineural invasion and metastasis. Unfortunately, the mechanisms underlying these processes and the signaling factors involved are largely unknown. In this study,...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Feng, Yujie, Hu, Xiao, Liu, Guangwei, Lu, Lianfang, Zhao, Wei, Shen, Fangzhen, Ma, Kai, Sun, Chuandong, Zhu, Chengzhan, Zhang, Bingyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219094/
https://ncbi.nlm.nih.gov/pubmed/30450012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0667-z
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