Tetraspanin 1 promotes epithelial-to-mesenchymal transition and metastasis of cholangiocarcinoma via PI3K/AKT signaling

BACKGROUND: Numerous studies have demonstrated that tetraspanin 1 (TSPAN1), a transmembrane protein, functions as an oncoprotein in many cancer types. However, its role and underlying molecular mechanism in cholangiocarcinoma (CCA) progression remain unclear. METHODS: In the present study, the expre...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Wang, Yan, Liang, Yingjian, Yang, Guangchao, Lan, Yaliang, Han, Jihua, Wang, Jiabei, Yin, Dalong, Song, Ruipeng, Zheng, Tongsen, Zhang, Shugeng, Pan, Shangha, Liu, Xirui, Zhu, Mingxi, Liu, Yao, Cui, Yifeng, Meng, Fanzheng, Zhang, Bo, Liang, Shuhang, Guo, Hongrui, Liu, Yufeng, Hassan, Md Khaled, Liu, Lianxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280496/
https://ncbi.nlm.nih.gov/pubmed/30514341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0969-y
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