Genetic variation determines VEGF-A plasma levels in cancer patients

Angiogenesis is essential in tumor biology and is regulated by vascular endothelial growth factor (VEGF) ligands and receptors. Here we aimed to discover genetic variants associated with levels of circulating angiogenic proteins in cancer patients. Plasma was collected at baseline in 216 pancreatic...

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Publicat a:Sci Rep
Autors principals: Innocenti, Federico, Jiang, Chen, Sibley, Alexander B., Etheridge, Amy S., Hatch, Ace J., Denning, Stefanie, Niedzwiecki, Donna, Shterev, Ivo D., Lin, Jiaxing, Furukawa, Yoichi, Kubo, Michiaki, Kindler, Hedy L., Auman, J. Todd, Venook, Alan P., Hurwitz, Herbert I., McLeod, Howard L., Ratain, Mark J., Gordan, Raluca, Nixon, Andrew B., Owzar, Kouros
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218528/
https://ncbi.nlm.nih.gov/pubmed/30397360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34506-4
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