Genetic variation determines VEGF-A plasma levels in cancer patients

Angiogenesis is essential in tumor biology and is regulated by vascular endothelial growth factor (VEGF) ligands and receptors. Here we aimed to discover genetic variants associated with levels of circulating angiogenic proteins in cancer patients. Plasma was collected at baseline in 216 pancreatic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Innocenti, Federico, Jiang, Chen, Sibley, Alexander B., Etheridge, Amy S., Hatch, Ace J., Denning, Stefanie, Niedzwiecki, Donna, Shterev, Ivo D., Lin, Jiaxing, Furukawa, Yoichi, Kubo, Michiaki, Kindler, Hedy L., Auman, J. Todd, Venook, Alan P., Hurwitz, Herbert I., McLeod, Howard L., Ratain, Mark J., Gordan, Raluca, Nixon, Andrew B., Owzar, Kouros
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218528/
https://ncbi.nlm.nih.gov/pubmed/30397360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34506-4
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