Preoperative Phosphorylated Tau Concentration in the Cerebrospinal Fluid Can Predict Cognitive Function Three Years after Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus

BACKGROUND: Idiopathic normal pressure hydrocephalus (iNPH) is commonly treated by cerebrospinal fluid (CSF) shunting. However, the long-term efficacy of shunt intervention in the presence of comorbid Alzheimer’s disease (AD) pathology is debated. OBJECTIVE: To identify AD-associated CSF biomarkers...

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Bibliografski detalji
Izdano u:J Alzheimers Dis
Glavni autori: Nakajima, Madoka, Miyajima, Masakazu, Ogino, Ikuko, Akiba, Chihiro, Kawamura, Kaito, Kamohara, Chihiro, Fusegi, Keiko, Harada, Yoshinao, Hara, Takeshi, Sugano, Hidenori, Tange, Yuichi, Karagiozov, Kostadin, Kasuga, Kensaku, Ikeuchi, Takeshi, Tokuda, Takahiko, Arai, Hajime
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218133/
https://ncbi.nlm.nih.gov/pubmed/30248058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180557
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